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Recent Publications

  1. Chung, CS, Kou, Y, Shemtov, SJ, Verheijen, BM, Flores, I, Love, K et al.. Transcript errors generate amyloid-like proteins in huwman cells. Nat Commun. 2024;15 (1):8676. doi: 10.1038/s41467-024-52886-2. PubMed PMID:39375347 PubMed Central PMC11458900.
  2. Huang, B, Zeng, Z, Kim, S, Fausto, CC, Koppitch, K, Li, H et al.. Long-term expandable mouse and human-induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and disease. Cell Stem Cell. 2024;31 (6):921-939.e17. doi: 10.1016/j.stem.2024.04.002. PubMed PMID:38692273 PubMed Central PMC11162329.
  3. Huang, B, Zeng, Z, Li, H, Li, Z, Chen, X, Guo, J et al.. Modeling kidney development, disease, and plasticity with clonal expandable nephron progenitor cells and nephron organoids. bioRxiv. 2023; :. doi: 10.1101/2023.05.25.542343. PubMed PMID:37293038 PubMed Central PMC10245960.
  4. Chung, C, Verheijen, BM, Zhang, X, Huang, B, Coakley, A, McGann, E et al.. The fidelity of transcription in human cells. Proc Natl Acad Sci U S A. 2023;120 (5):e2210038120. doi: 10.1073/pnas.2210038120. PubMed PMID:36696440 PubMed Central PMC9945944.
  5. Li, Z, Lindström, NO. Building a kidney tree: Functional collecting duct from human pluripotent stem cells. Dev Cell. 2022;57 (19):2251-2253. doi: 10.1016/j.devcel.2022.09.009. PubMed PMID:36220079 .
  6. Yuan, B, Zhou, X, Suzuki, K, Ramos-Mandujano, G, Wang, M, Tehseen, M et al.. Author Correction: Wiskott-Aldrich syndrome protein forms nuclear condensates and regulates alternative splicing. Nat Commun. 2022;13 (1):5291. doi: 10.1038/s41467-022-32875-z. PubMed PMID:36075901 PubMed Central PMC9458650.
  7. Huang, B, Zeng, Z, Zhang, CC, Schreiber, ME, Li, Z. Approaches to kidney replacement therapies-opportunities and challenges. Front Cell Dev Biol. 2022;10 :953408. doi: 10.3389/fcell.2022.953408. PubMed PMID:35982852 PubMed Central PMC9380013.
  8. Yuan, B, Zhou, X, Suzuki, K, Ramos-Mandujano, G, Wang, M, Tehseen, M et al.. Wiskott-Aldrich syndrome protein forms nuclear condensates and regulates alternative splicing. Nat Commun. 2022;13 (1):3646. doi: 10.1038/s41467-022-31220-8. PubMed PMID:35752626 PubMed Central PMC9233711.
  9. Zeng, Z, Huang, B, Parvez, RK, Li, Y, Chen, J, Vonk, AC et al.. Generation of patterned kidney organoids that recapitulate the adult kidney collecting duct system from expandable ureteric bud progenitors. Nat Commun. 2021;12 (1):3641. doi: 10.1038/s41467-021-23911-5. PubMed PMID:34131121 PubMed Central PMC8206157.
  10. Tsujimoto, H, Kasahara, T, Sueta, SI, Araoka, T, Sakamoto, S, Okada, C et al.. A Modular Differentiation System Maps Multiple Human Kidney Lineages from Pluripotent Stem Cells. Cell Rep. 2020;31 (1):107476. doi: 10.1016/j.celrep.2020.03.040. PubMed PMID:32268094 .
  11. Huang, B, Liu, Z, Vonk, A, Zeng, Z, Li, Z. Epigenetic regulation of kidney progenitor cells. Stem Cells Transl Med. 2020;9 (6):655-660. doi: 10.1002/sctm.19-0289. PubMed PMID:32163228 PubMed Central PMC7214665.
  12. Li, Z, Araoka, T, Belmonte, JCI. Gene Editing in 3D Cultured Nephron Progenitor Cell Lines. Methods Mol Biol. 2019;1926 :151-159. doi: 10.1007/978-1-4939-9021-4_13. PubMed PMID:30742270 .
  13. Yang, Y, Liu, B, Xu, J, Wang, J, Wu, J, Shi, C et al.. Derivation of Pluripotent Stem Cells with In Vivo Embryonic and Extraembryonic Potency. Cell. 2017;169 (2):243-257.e25. doi: 10.1016/j.cell.2017.02.005. PubMed PMID:28388409 PubMed Central PMC5679268.
  14. Wang, L, Xu, X, Cao, Y, Li, Z, Cheng, H, Zhu, G et al.. Activin/Smad2-induced Histone H3 Lys-27 Trimethylation (H3K27me3) Reduction Is Crucial to Initiate Mesendoderm Differentiation of Human Embryonic Stem Cells. J Biol Chem. 2017;292 (4):1339-1350. doi: 10.1074/jbc.M116.766949. PubMed PMID:27965357 PubMed Central PMC5270477.
  15. Li, Z, Araoka, T, Wu, J, Liao, HK, Li, M, Lazo, M et al.. 3D Culture Supports Long-Term Expansion of Mouse and Human Nephrogenic Progenitors. Cell Stem Cell. 2016;19 (4):516-529. doi: 10.1016/j.stem.2016.07.016. PubMed PMID:27570066 PubMed Central PMC7832086.