Recent Publications

  1. Li, Z, Araoka, T, Belmonte, JCI. Gene Editing in 3D Cultured Nephron Progenitor Cell Lines. Methods Mol. Biol. 2019;1926 :151-159. doi: 10.1007/978-1-4939-9021-4_13. PubMed PMID:30742270 .
  2. Yang, Y, Liu, B, Xu, J, Wang, J, Wu, J, Shi, C et al.. Derivation of Pluripotent Stem Cells with In Vivo Embryonic and Extraembryonic Potency. Cell. 2017;169 (2):243-257.e25. doi: 10.1016/j.cell.2017.02.005. PubMed PMID:28388409 PubMed Central PMC5679268.
  3. Wang, L, Xu, X, Cao, Y, Li, Z, Cheng, H, Zhu, G et al.. Activin/Smad2-induced Histone H3 Lys-27 Trimethylation (H3K27me3) Reduction Is Crucial to Initiate Mesendoderm Differentiation of Human Embryonic Stem Cells. J. Biol. Chem. 2017;292 (4):1339-1350. doi: 10.1074/jbc.M116.766949. PubMed PMID:27965357 PubMed Central PMC5270477.
  4. Li, Z, Araoka, T, Wu, J, Liao, HK, Li, M, Lazo, M et al.. 3D Culture Supports Long-Term Expansion of Mouse and Human Nephrogenic Progenitors. Cell Stem Cell. 2016;19 (4):516-529. doi: 10.1016/j.stem.2016.07.016. PubMed PMID:27570066 .
  5. Zhu, G, Fei, T, Li, Z, Yan, X, Chen, YG. Activin Regulates Self-renewal and Differentiation of Trophoblast Stem Cells by Down-regulating the X Chromosome Gene Bcor. J. Biol. Chem. 2015;290 (36):22019-29. doi: 10.1074/jbc.M115.674127. PubMed PMID:26221038 PubMed Central PMC4571955.
  6. Wu, J, Okamura, D, Li, M, Suzuki, K, Luo, C, Ma, L et al.. An alternative pluripotent state confers interspecies chimaeric competency. Nature. 2015;521 (7552):316-21. doi: 10.1038/nature14413. PubMed PMID:25945737 PubMed Central PMC5278765.
  7. Zhang, J, Fei, T, Li, Z, Zhu, G, Wang, L, Chen, YG et al.. BMP induces cochlin expression to facilitate self-renewal and suppress neural differentiation of mouse embryonic stem cells. J. Biol. Chem. 2013;288 (12):8053-60. doi: 10.1074/jbc.M112.433995. PubMed PMID:23344953 PubMed Central PMC3605624.
  8. Li, Z, Chen, YG. Functions of BMP signaling in embryonic stem cell fate determination. Exp. Cell Res. 2013;319 (2):113-9. doi: 10.1016/j.yexcr.2012.09.016. PubMed PMID:23051821 .
  9. Li, Z, Chen, YG. Fine-tune of intrinsic ERK activity by extrinsic BMP signaling in mouse embryonic stem cells. Protein Cell. 2012;3 (6):401-4. doi: 10.1007/s13238-012-2925-5. PubMed PMID:22528752 PubMed Central PMC4875488.
  10. Chen, YG, Li, Z, Wang, XF. Where PI3K/Akt meets Smads: the crosstalk determines human embryonic stem cell fate. Cell Stem Cell. 2012;10 (3):231-2. doi: 10.1016/j.stem.2012.02.008. PubMed PMID:22385648 PubMed Central PMC3586792.